Everything Not Forbidden Is Compulsory
Jesse Walker | January 31, 2007, 11:35am
When we last
checked in on Gardasil, a vaccine against viruses that cause cervical cancer, the issue was whether the treatment would be allowed at all. HPV viruses are transmitted sexually, and the shot is
most effective when given to girls aged 10 to 14; opponents argued that it might encourage preteen promiscuity.
Now the issue is whether the vaccination should be
required. Since Gardasil was
approved, several states have been mulling mandates for middle-school girls to get the shots. In Maryland, the legislator who sponsored such a bill has just
withdrawn it from consideration.
So far, the loudest opposition to these bills has come from religious-right groups like
Focus on the Family, which "supports widespread (universal) availability of HPV vaccines but opposes mandatory HPV vaccinations for entry to public school" because "the decision of whether to vaccinate a minor against this or other sexually transmitted infections should remain with the child's parent or guardian." The drive to require the shots has largely come from the pharmaceutical company Merck, which -- surprise! -- manufactures the vaccine. The larger medical community has been cooler to the idea, as the Baltimore
Sun reported Monday:
The American Academy of Pediatrics, for instance, is urging a go-slow approach, with an initial focus on raising public awareness of HPV and more monitoring of the safety of the vaccine, which had minimal side effects in clinical trials but hasn't been observed in larger-scale rollouts.
"A lot of us are worried it's a little early to be pushing a mandated HPV vaccine," said Dr. Martin Myers, director of the National Network for Immunization Information. "It's not that I'm not wildly enthusiastic about this vaccine. I am. But many of us are concerned a mandate may be premature, and it's important for people to realize that this isn't as clear-cut as with some previous vaccines."
He added, "It's not the vaccine community pushing for this."
The stakes here weren't quite as high as the rhetoric on either side might suggest. Without the Maryland bill, the vaccine will still be available on a voluntary basis. With the bill, parents could receive a religious exemption from its requirements; and if you aren't religious, you could still probably get the exemption if you want it, since the only thing you
need to do is sign a form. So the vaccinations would have been more a default setting than an absolute mandate.
But the stench of corporate welfare is still in the air, and so is the smell of social engineering. The terms of the debate have shifted; the issue now is not whether the government should deny us a vaccine that could save lives, but whether it should push it on people who don't want it. You can count me with the fundies on that one.
Captain Holly | February 1, 2007, 1:24pm | #
I'm not usually one to see corporate conspiracies in every corner, but the HPV vaccine is probably the most over-hyped and expensive medical treatment to come down the pike recently. I can't help but wonder how many of the vaccine proponents own Merck stock.
To review, there are about 100 strains of HPV, about 30 of which can be sexually transmitted. But only 6 of those strains are associated with genital warts and cervical cancer. The rest result in mild, self-limiting infections that are quite often unnoticed by the infected person.
The hysterical statistic that most women have been infected with HPV by age 50 has two big caveats: It is describing sexually-active, non-monogamous women, and it takes into account infections by all types of HPV, not just the cancer-causing ones.
But hey, it prevents cancer, so why not use it? Well, not quite: The vaccine only protects against 4 of the 6 cancer-associated strains, those that cause roughly 70% of cervical cancer. So even though you may get vaccinated, it doesn't eliminate your chances of getting cervical cancer.
Which is why even women who have been vaccinated are still advised to have yearly Pap smears once they become sexually active.
But hey, reducing cancer risk by some 70% is a big thing because cervical cancer is so widespread. Well, no. Cervical cancer isn't even in the Top 10 of either most common or most fatal cancers. And both the death rates and incidence rates of cervical cancer have been steadily dropping for the past 30 years, largely due to...Pap smears.
Then there's a very un-PC secret about cervical cancer: It occurs much more frequently in lower-income and minority women. The average white middle-class teenage girl whose parents would be able to afford the vaccine is statistically the least likely person to get HPV.
And finally, it doesn't protect against any other type of STD, meaning that women who get the vaccine will still have to protect take steps to protect themselves, steps that will also prevent HPV infection in the first place.
So in summary, you have a very expensive vaccine that protects against a disease that isn't very easily transmitted, that doesn't even protect against all forms of the disease, that still requires the recipient to behave as if they hadn't been vaccinated, and that protects against a cancer that is already both relatively uncommon and easily preventable. To me, that's a relatively small benefit at a relatively large cost.
Oh, and all the above facts were taken from those hotbeds of Right-Wing Christer Activism: the Centers for Disease Control and the National Cancer Institute. See http://www.cdc.gov/nip/vaccine/hpv/hpv-faqs.htm#5 and http://www.cancer.gov/cancertopics/types/cervical/.
stickdog | February 4, 2007, 5:44pm | #
The Facts About GARDASIL
1) GARDASIL is a vaccine for 4 strains of the human papillomavirus (HPV), two strains that are strongly associated (and probably cause) genital warts and two strains that are typically associated (and may cause) cervical cancer. About 90% of people with genital warts show exposure to one of the two HPV strains strongly suspected to cause genital warts. About 70% of women with cervical cancer show exposure to one of the other two HPV strains that the vaccine is designed to confer resistance to.
2) HPV is a sexually communicable (not an infectious) virus. When you consider all strains of HPV, over 70% of sexually active males and females have been exposed. A condom helps a lot (70% less likely to get it), but has not been shown to stop transmission in all cases (only one study of 82 college girls who self-reported about condom use has been done). For the vast majority of women, exposure to HPV strains (even the four “bad ones” protected for in GARDASIL) results in no known health complications of any kind.
3) Cervical cancer is not a deadly nor prevalent cancer in the US or any other first world nation. Cervical cancer rates have declined sharply over the last 30 years and are still declining. Cervical cancer accounts for less than 1% of of all female cancer cases and deaths in the US. Cervical cancer is typically very treatable and the prognosis for a healthy outcome is good. The typical exceptions to this case are old women, women who are already unhealthy and women who don’t get pap smears until after the cancer has existed for many years.
4) Merck’s clinical studies for GARDASIL were problematic in several ways. Only 20,541 women were used (half got the “placebo”) and their health was followed up for only four years at maximum and typically 1-3 years only. More critically, only 1,121 of these subjects were less than 16. The younger subjects were only followed up for a maximum of 18 months. Furthermore, less than 10% of these subjects received true placebo injections. The others were given injections containing an aluminum salt adjuvant (vaccine enhancer) that is also a component of GARDASIL. This is scientifically preposterous, especially when you consider that similar alum adjuvants are suspected to be responsible for Gulf War disease and other possible vaccination related complications.
5) Both the “placebo” groups and the vaccination groups reported a myriad of short term and medium term health problems over the course of their evaluations. The majority of both groups reported minor health complications near the injection site or near the time of the injection. Among the vaccination group, reports of such complications were slightly higher. The small sample that was given a real placebo reported far fewer complications — as in less than half. Furthermore, most if not all longer term complications were written off as not being potentially vaccine caused for all subjects.
6) Because the pool of test subjects was so small and the rates of cervical cancer are so low, NOT A SINGLE CONTROL SUBJECT ACTUALLY CONTRACTED CERVICAL CANCER IN ANY WAY, SHAPE OR FORM — MUCH LESS DIED OF IT. Instead, this vaccine’s supposed efficacy is based on the fact that the vaccinated group ended up with far fewer cases (5 vs. about 200) of genital warts and “precancerous lesions” (dysplasias) than the alum injected “control” subjects.
7) Because the tests included just four years of follow up at most, the long term effects and efficacy of this vaccine are completely unknown for anyone. All but the shortest term effects are completely unknown for little girls. Considering the tiny size of youngster study, the data about the shortest terms side effects for girls are also dubious.
8) GARDASIL is the most expensive vaccine ever marketed. It requires three vaccinations at $120 a pop for a total price tag of $360. It is expected to be Merck’s biggest cash cow of this and the next decade.
These are simply the facts of the situation as presented by Merck and the FDA.