Rotten to the Mevacor
Kerry Howley | December 12, 2007, 3:37pm
Merck is once again trying to sell its widely prescribed statin, Mevacor, over the counter, and an FDA advisory panel is listening to arguments today. (I wrote about Merck's second doomed attempt to do the same back in 2005 for my first Reason feature) As one cardiologist told me then, "We're talking about the thing that kills more people than any other disease in America...We're talking about millions of lives saved." Merck has sold a statin OTC in Britain for years now.
The FDA confirms that Mevacor is effective and extremely safe if used properly, but has long doubted the ability of consumers to read directions and follow them. ABC News finds a long list of selfless, kindly cardiologists with absolutely no interest in the status quo to argue that consumers can't possibly deal with their cholesterol problems without... the help of a cardiologist. Also, drug companies are profit-driven. Not like cardiologists.
"I think this is a very clear call," said Dr. Steve Nissen, chairman of cardiovascular medicine at the Cleveland Clinic Foundation and immediate past-president of the American College of Cardiology. "I do not think it is a good idea."
"OTC [over-the-counter] statins would be a very bad idea," agreed Dr. John Messmer, associate professor of medicine at the Penn State College of Medicine in Palmyra.
"While it is true that statins are indeed quite safe despite rumors to the contrary ... when a drug is available OTC the user should be able to judge whether it has had the desired effect. The nonmedical person is not in the position to decide if his or her cholesterol is low enough."
Dr. Douglas Zipes, distinguished professor of cardiology at the Indiana University School of Medicine in Indianapolis, agreed that the possible side effects of the drug lend weight to the argument that it should not be available without a prescription.
"[The] dangers are that it may prevent people from seeing a cardiologist and not getting a proper evaluation for their heart disease," Zipes said.
And patients who lack health insurance and can't afford the doctors' visits or the price of a prescription drug? Oh well.
Paul | December 12, 2007, 6:52pm | #
you know who:
Thank you for the link.
My first comment is what you've done is provided a link to possible issues with one subclass of "psychiatric drugs", particularly anti-depressants. This does not even begin to cover the large array of drugs provided to people with all manner of psychoses such as schizo-effective disorder, etc. So your broad statement of "psychiatric drugs" is still wanting.
However, even the article you provide doesn't paint this issue as a slam-dunk. For instance, there are statistically significant differences between the anti-depressant and placebo. Just not "clinically significant".
However, you've cherry picked one of the major areas which is a notoriously "fuzzy" segment of psychiatric "illness". Depression in many ways is much like back and neck pain-- two things which also respond very well to placebo and acupuncture (real or fake).
I would point out that the drugs covered are for depression specifically, not bi-polar. The manic side of bipolar disorder is often treated with Lithium. Lithium is very affective vs. placebo, for instance.
Also, you "know" your bipolar was caused by a drug. From the very site you use as an authoritative source:
The cause of bipolar disorder is not entirely known. Genetic, neurochemical and environmental factors probably interact at many levels to play a role in the onset and progression of bipolar disorder. The current thinking is that this is a predominantly biological disorder that occurs in a specific part of the brain and is due to a malfunction of the neurotransmitters (chemical messengers in the brain). As a biological disorder, it may lie dormant and be activated spontaneously or it may be triggered by stressors in life.
Problem here, you-know-who, is that I have personal experience with bi-polar disorder, and believe me, it was there
before medication was taken, not after.
BakedPenguin:
No one here who knows one whit about psychiatric medications believe they're a walk in the park. Many have severe side effects, but to label them all as no more effective than placebo, then go and talk about what effects they have is... sorry for this... nutty. Antipsychotics are often times as bad as the disease, but when you've got a man walking naked down the street, muttering to himself, giving him a medication that gives him body ticks and makes him unable to regulate his body temperature is, alas, the lesser of two evils.